ANALYTYKA Fine Chemicals and Pharmaceutical Raw Materials

Caffeine anhydrous (RFE, USP, BP, Ph. Eur.) PRS


C8H10N4O2



 

M.= 194,19 CAS [58-08-2] EINECS 200-362-1
NC 2939 30 00    


SYNONYMS: 7-Methyltheobromine · 3,7-Dihydro-1,3,7-Trimethyl-1H-Purin-2,6-Dione · 1,3,7-Trimethylxantine ·
PHYSICAL DATA: White crystals or crystalline powder · Solubility in water at 20 ° C 22 g/l · D: 1,23 · M. P.: 238 ° C · pH 1% solution: 6,9 ·
 

HAZARDOUS: E.C.: 613-086-00-5 · RTECS: EV 7465000 · LD50 oral rat 192 mg/Kg · LD L0 oral hmn 192 mg/Kg ·

   R: 25
S: 45

TRANSPORT REGULATIONS: UN: 1544 · ADR: 6.1/III · IMDG: 6.1/III · IATA: 6.1/III · PAX: 619 · CAO: 619·

SPECIFICATIONS:

Assay (Perchl. Ac.) calc. a.d.s 98,5-101,0%
Identity according to Pharmacopoeias p/t.
Melting range (a.d.s.) 235-237,5°C

MAXIMUM LIMIT OF IMPURITIES		   
Appearance of solution p/t.
Insoluble matter in H2O p/t.
Loss on drying 0,5 %
Residue on ignition (as SO4) 0,1 %
Darkened substances by H2SO4 p/t.
Related substances p/t.
Organic volatile impurities p/t.
Chromatographic purity p/t.
Other alkaloids p/t.
Acidity p/t.
Sulphate (SO4) 0,05 %
Heavy metals (as Pb) 0,001 %
As 0,0003 %
Cu 0,001 %
Fe 0,002 %
Ni 0,001 %
Pb 0,001 %