1. Product Identification
Synonyms: m-Nitroaniline; 3-Nitrobenzenamine; 3-Nitrophenylamine
CAS No.: 99-09-2
Molecular Weight: 138.0542
Product Codes: N0038
2. Composition/Information on Ingredients
Caution! Possible risks of irreversible effects. Methemoglobin
former - can cause cyanosis. May cause eye and skin irritation. May cause
respiratory and digestive tract irritation. May be harmful if swallowed. This
substance has caused adverse reproductive and fetal effects in animals.
Target Organs: Blood, kidneys, liver, blood forming organs.
Potential Health Effects
Eye: May cause eye irritation. Vapors may cause eye irritation.
May cause eye injury.
Skin: May cause skin irritation. Substance is rapidly absorbed
through the skin. If absorbed, may cause symptoms similar to those for
Ingestion: May cause methemoglobinemia, cyanosis (bluish
discoloration of skin due to deficient oxygenation of the blood), convulsions,
and death. Effects may be delayed 2 to 4 hours. Methemoglobinemia is
characterized by dizziness, drowsiness, headache, shortness of breath, cyanosis
(bluish discoloration of skin due to deficient oxygenation of the blood), rapid
heart rate and chocolate-brown colored blood. May be harmful if swallowed.
Alcohol can intensify effects.
Inhalation: May cause respiratory tract irritation. May cause
effects similar to those described for ingestion. Inhalation of aniline causes
anoxia due to the formation of methemoglobin.
Chronic: May cause liver and kidney damage. May cause bone
marrow abnormalities with damage to blood forming tissues. May cause anemia and
other blood cell abnormalities. Repeated exposure may cause central nervous
system damage. Adverse reproductive effects have been reported in animals.
4. First Aid
Eyes: Immediately flush eyes with plenty of water for at least
15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid
Skin: Get medical aid immediately. Flush skin with plenty of
water for at least 15 minutes while removing contaminated clothing and shoes.
Wash clothing before reuse.
Ingestion: Call a poison control center. If swallowed, do not
induce vomiting unless directed to do so by medical personnel. Never give
anything by mouth to an unconscious person. Get medical aid.
Inhalation: Get medical aid immediately. Remove from exposure
and move to fresh air immediately. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen.
Notes to Physician: Absorption of this product into the body
may cause cyanosis (bluish discoloration of skin due to deficient oxygenation of
the blood). Moderate degrees of cyanosis need to be treated only by supportive
measures: bed rest and oxygen inhalation. For methemoglobinemia, administer
oxygen alone or with Methylene Blue depending on the methemoglobin concentration
in the blood. Cleansing of the entire contaminated area of the body is of utmost
Antidote: Methylene blue, alone or in combination with oxygen
is indicated as a treatment in nitrite induced methemoglobinemia.
5. Fire Fighting
General Information: As in any fire, wear a self-contained
breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and
full protective gear. During a fire, irritating and highly toxic gases may be
generated by thermal decomposition or combustion. Vapors may be heavier than
air. They can spread along the ground and collect in low or confined areas. May
decompose explosively when heated or involved in a fire.
Extinguishing Media: In case of fire, use water, dry chemical,
chemical foam, or alcohol-resistant foam. Use agent most appropriate to
Flash Point: Not applicable.
Autoignition Temperature: 521 deg C ( 969.80 deg F)
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 3; Flammability: 1;
6. Accidental Release Measures
General Information: Use proper personal protective equipment
as indicated in Section 8.
Spills/Leaks: Vacuum or sweep up material and place into a
suitable disposal container. Clean up spills immediately, observing precautions
in the Protective Equipment section. Wear a self contained breathing apparatus
and appropriate personal protection. (See Exposure Controls, Personal Protection
section). Avoid generating dusty conditions. Remove all sources of ignition.
7. Handling and
Handling: Wash thoroughly after handling. Remove contaminated
clothing and wash before reuse. Use with adequate ventilation. Ground and bond
containers when transferring material. Use spark-proof tools and explosion proof
equipment. Keep container tightly closed. Do not get on skin or in eyes. Do not
ingest or inhale.
Storage: Keep away from sources of ignition. Store in a cool,
dry, well-ventilated area away from incompatible substances.
Controls, Personal Protection
Engineering Controls: Use adequate general or local exhaust
ventilation to keep airborne concentrations below the permissible exposure
OSHA - Final PELs
OSHA Vacated PELs: 3-Nitroaniline: No OSHA Vacated PELs are
listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety
goggles as described by OSHA's eye and face protection regulations in 29 CFR
1910.133 or European Standard EN166.
Skin: Wear appropriate gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin
Respirators: Follow the OSHA respirator regulations found in 29 CFR
1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN
149 approved respirator if exposure limits are exceeded or if irritation or
other symptoms are experienced.
9. Physical and
Physical State: Solid
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Vapor Density: 4.8
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 306 deg C
Freezing/Melting Point:114 deg C
Decomposition Temperature:> 396 deg C
Solubility: Insoluble in water.
Specific Gravity/Density:Not available.
10. Stability and
Chemical Stability: Stable. However, may decompose if heated.
Conditions to Avoid: High temperatures, ignition sources, dust
generation, excess heat.
Incompatibilities with Other Materials: Strong acids, strong oxidizing
agents, strong reducing agents.
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide,
irritating and toxic fumes and gases, carbon dioxide, nitrogen.
Hazardous Polymerization: Has not been reported.
CAS# 99-09-2: BY6825000
Oral, mouse: LD50 = 308 mg/kg;
Oral, rat: LD50 = 535 mg/kg;
CAS# 99-09-2: Not listed by ACGIH, IARC, NTP, or CA Prop 65.
Epidemiology: Animal studies have demonstrated fetoxicity (growth
retardation) and teratogenicity (exencephaly, angulated ribs, dilated brain
Teratogenicity: No information available.
Reproductive Effects: No information available.
Mutagenicity: No information available.
Neurotoxicity: No information available.
Ecotoxicity: No data available. No information available.
Environmental: No information available.
Physical: No information available.
Chemical waste generators must determine whether a discarded
chemical is classified as a hazardous waste. US EPA guidelines for the
classification determination are listed in 40 CFR Parts 261.3. Additionally,
waste generators must consult state and local hazardous waste regulations to
ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
CAS# 99-09-2 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
CAS # 99-09-2: immediate, delayed, reactive.
Section 313 No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants.
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances
under the CWA.
None of the chemicals in this product are listed as Priority Pollutants
under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants under
None of the chemicals in this product are considered highly hazardous by
CAS# 99-09-2 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
California Prop 65
California No Significant Risk Level: None of the chemicals in this product are
European Labeling in Accordance with EC Directives
R 23/24/25 Toxic by inhalation, in contact with skin and if
R 33 Danger of cumulative effects.
R 52/53 Harmful to aquatic organisms, may cause long-term adverse
effects in the aquatic environment.
S 28 After contact with skin, wash immediately with...
S 36/37 Wear suitable protective clothing and gloves.
S 45 In case of accident or if you feel unwell, seek medical advice
immediately (show the label where possible).
S 28B After contact with skin, wash immediately with plenty of water
S 61 Avoid release to the environment. Refer to special instructions
/safety data sheets.
WGK (Water Danger/Protection)
CAS# 99-09-2: 2
Canada - DSL/NDSL
CAS# 99-09-2 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of D1A, D2A.
This product has been classified in accordance with the hazard criteria of the
Controlled Products Regulations and the MSDS contains all of the information
required by those regulations.
Canadian Ingredient Disclosure List
CAS# 99-09-2 is listed on the Canadian Ingredient Disclosure List.
16. Other Information
ANALYTYKA provides the information contained herein in good faith but makes
no representation as to its comprehensiveness or accuracy. This document is
intended only as a guide to the appropriate precautionary handling of the
material by a properly trained person using this product. Individuals
receiving the information must exercise their independent judgment in
determining its appropriateness for a particular purpose. ANALYTYKA MAKES NO
REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT
LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR
PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT TO
WHICH THE INFORMATION REFERS. ACCORDINGLY, ANALYTYKA WILL NOT BE RESPONSIBLE FOR
DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.