2,2-Bis(hydroxymethyl)-2,2',2''-nitrilotriethanol

ANALYTYKA Fine Chemicals and Pharmaceutical Raw Materials


2,2-Bis(hydroxymethyl)-2,2',2''-nitrilotriethanol


1. Product Identification

Synonyms: Bis(2-hydroxyethyl)iminotris(hydroxymethyl)methane; BIS-TRIS
CAS No.: 6976-37-0
Molecular Weight: 209.24
Chemical Formula: C8H19NO5
Product Codes: B0077

2. Composition/Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
6976-37-0 2,2-Bis(hydroxymethyl)-2,2',2''-nitrilotriethanol 98+ 230-237-7

 


3. Hazards Identification


 EMERGENCY OVERVIEW

Appearance: white powder.
Warning! Causes eye, skin, and respiratory tract irritation. Corrosive to metal.
Target Organs: Respiratory system, eyes, skin.


Potential Health Effects
Eye: Causes eye irritation.
Skin: Causes skin irritation. May be harmful if absorbed through the skin.
Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation: Causes respiratory tract irritation. May be harmful if inhaled.
Chronic: No information found.


4. First Aid Measures



Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin: Get medical aid. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion: Do not induce vomiting. Get medical aid.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Treat symptomatically and supportively.


5. Fire Fighting Measures



General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or appropriate foam.
Flash Point: Not applicable.
Autoignition Temperature: Not applicable.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 2; Flammability: 1; Instability: 0


6. Accidental Release Measures



General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Avoid generating dusty conditions. Provide ventilation. Do not let this chemical enter the environment.


7. Handling and Storage



Handling: Use with adequate ventilation. Minimize dust generation and accumulation. Do not get in eyes, on skin, or on clothing. Do not ingest or inhale. This product is corrosive to some metals. Do not use containers or equipment containing aluminum, magnesium, zinc, cadmium, or other alloys.
Storage: Store in a cool, dry place. Store in a tightly closed container. Corrosives area. Do not store in metal containers.


8. Exposure Controls, Personal Protection



Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
2,2-Bis(hydroxymethyl)-2,2',2''-nitrilotriethanol none listed none listed none listed

OSHA Vacated PELs: 2,2-Bis(hydroxymethyl)-2,2',2''-nitrilotriethanol: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.


9. Physical and Chemical Properties



Physical State: Powder
Appearance: white
Odor: none reported
pH: 8.8 - 9.6 (1% aq.sol.)
Vapor Pressure: Negligible.
Vapor Density: Not available.
Evaporation Rate:Negligible.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point:103 - 104 deg C
Decomposition Temperature:Not available.
Solubility: Soluble.
Specific Gravity/Density:Not available.
Molecular Formula:C8H19NO5
Molecular Weight:209.24


10. Stability and Reactivity



Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Incompatible materials, dust generation, metals, excess heat.
Incompatibilities with Other Materials: Strong oxidizing agents, strong acids, aluminum, brass, copper.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides (NOx) and ammonia (NH3).
Hazardous Polymerization: Will not occur.


11. Toxicological Information



RTECS#:      
CAS# 6976-37-0 unlisted.
LD50/LC50:
Not available.

Carcinogenicity:
CAS# 6976-37-0: Not listed by ACGIH, IARC, NTP, or CA Prop 65.

Epidemiology: No information found
Teratogenicity: No information found
Reproductive Effects: No information found
Mutagenicity: No information found
Neurotoxicity: No information found
Other Studies:


12. Ecological Information



Ecotoxicity: No data available. No information available.
Environmental: No information available.
Physical: No information available.
Other: Do not empty into drains.


13. Disposal Considerations


Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.


14. Transport Information


 
  US DOT Canada TDG
Shipping Name: AMINES, SOLID, CORROSIVE, N.O.S. AMINES, SOLID, CORROSIVE, N.O.S.
Hazard Class: 8 8
UN Number: UN3259 UN3259
Packing Group: III III

 


15. Regulatory Information


US FEDERAL

TSCA
     CAS# 6976-37-0 is listed on the TSCA inventory.
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
Section 313      No chemicals are reportable under Section 313.
Clean Air Act:
     This material does not contain any hazardous air pollutants.
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
     None of the chemicals in this product are listed as Hazardous Substances under the CWA.
     None of the chemicals in this product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
     None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
     CAS# 6976-37-0 is not present on state lists from CA, PA, MN, MA, FL, or NJ.

California Prop 65

California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations

European Labeling in Accordance with EC Directives
Hazard Symbols:
     XI
Risk Phrases:

     R 36/37/38 Irritating to eyes, respiratory system and skin.

Safety Phrases:

     S 26 In case of contact with eyes, rinse immediately with plenty of
     water and seek medical advice.
     S 37/39 Wear suitable gloves and eye/face protection.

WGK (Water Danger/Protection)

     CAS# 6976-37-0: No information available.
Canada - DSL/NDSL
     CAS# 6976-37-0 is listed on Canada's NDSL List.
Canada - WHMIS
     This product has a WHMIS classification of Not controlled..
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
 


16. Other Information

Product Use:
Laboratory Reagent.
Revision Information:
Jan. 2008.
Disclaimer:
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ANALYTYKA provides the information contained herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. ANALYTYKA MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, ANALYTYKA WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.
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